Thermo Fisher Scientific PTMA Polyclonal Antibody
인간 PTMA 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot, IHC, Flow Cytometry 등에 사용 가능. KLH 결합 합성 펩타이드(1–31 aa)를 면역원으로 제작. 고순도 Protein A 및 항원 친화 크로마토그래피 정제. 연구용으로만 사용.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:100 |
| Flow Cytometry (Flow) | Assay-dependent |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between 1–31 amino acids from the N-terminal region of human PTMA |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 2 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2717434 |
Target Information
The thymus gland produces several hormones or hormone-like substances derived from a polypeptide precursor known as prothymosin-alpha. In the rat, this precursor contains 113 amino acids. A peptide containing 28 amino acid residues, named thymosin-alpha-1, was originally isolated from calf thymosin fraction 5 and shown to restore immune function in various in vitro and in vivo test systems. Thymosin-alpha-1 was later isolated from human thymosin and found to have the same amino acid sequence as bovine thymosin-alpha-1.
In 2003, Jiang et al. identified a pathway regulating mitochondria-initiated caspase activity. In this pathway, putative human HLA class II-associated protein (PHAP) promoted caspase-9 activation after apoptosome formation, whereas prothymosin-alpha-1 negatively regulated caspase-9 activation by inhibiting apoptosome formation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
제품 이미지
- PA5-71580_PTMA_P06454-1_Rabbit.svg
- PA5-71580_PTMA_P06454-1_Rabbit_PDP.jpeg
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