Thermo Fisher Scientific Fra1 Polyclonal Antibody
Fra1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 고순도 친화 크로마토그래피 정제, 1 mg/mL 농도, PBS 및 50% glycerol 저장. 연구용 전용.
- 판매단위
- pk
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50–1:200 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthesized peptide derived from human FOSL1 (Accession P15407), corresponding to amino acid residues R111–L161 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2899888 |
Product Specific Information
Antibody detects endogenous levels of total FRA1.
Target Information
The v-Fos oncogene was initially detected in two independent murine osteosarcoma virus isolates and an avian nephroblastoma virus. Members of the c-Fos gene family, including c-Fos, Fos B, Fra-1, and Fra-2, encode nuclear phosphoproteins that are rapidly and transiently induced by various agents and function as transcriptional regulators for several genes. In contrast to c-Jun proteins, which form homo- and heterodimers binding to specific DNA response elements, c-Fos proteins are only active as heterodimers with members of the Jun gene family. Additionally, selected ATF/CREB family members can form leucine zipper dimers with Fos and Jun, exhibiting differential specificity and affinity for AP-1 and CRE sites.
For Research Use Only.
Not for use in diagnostic procedures. Not for resale without express authorization.
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