Thermo Fisher Scientific Nectin 3 Polyclonal Antibody
Thermo Fisher Scientific의 Nectin 3 Polyclonal Antibody는 인간, 마우스, 랫트에서 반응하며 Western blot에 최적화된 고품질 항체입니다. 항원 친화 크로마토그래피로 정제되었으며, 1 mg/mL 농도의 액상 형태로 제공됩니다. 세포 간 접착 단백질 Nectin-3 연구에 적합합니다.
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Applications
- Western Blot (WB): Tested dilution 1:5,000–1:20,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein fragment corresponding to amino acids 115–353 of Human Nectin 3 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2545413 |
Product Specific Information
- Recommended positive controls: K562, THP-1, mouse brain, rat brain
- Predicted reactivity: Mouse (95%), Rat (94%)
- Store product as a concentrated solution. Centrifuge briefly prior to opening the vial.
Target Information
Nectin-3 is an 83 kDa type I transmembrane glycoprotein, belonging to the immunoglobulin superfamily of cell-cell adhesion molecules. Nectins (1–4) mediate calcium-independent cell-cell adhesion and participate in forming diverse junctions such as adherens junctions, synaptic junctions, and Sertoli cell-spermatid junctions.
Nectin-3 (also known as PRR3) is predominantly expressed in testis and placental tissues and interacts with afadin and CD155. It plays an important role in maintaining cell-cell junction integrity and spermatid maturation.
주의사항
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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