Thermo Fisher Scientific POM121 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

1:1,000-1:3,000

-

Immunocytochemistry (ICC/IF)

1:100-1:500

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

A synthesized peptide derived from human POM121(Accession Q96HA1), corresponding to amino acid residues P1216-K1249. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:POM121,uniProtId:A6NF01-1,ncbiNodeId:9606,antigenRange:834,antigenLength:834,antigenImageFileName:PA5-103243_POM121_A6NF01-1_Rabbit.svg,antigenImageFileNamePDP:PA5-103243_POM121_A6NF01-1_Rabbit_PDP.jpeg,sortOrder:1},{targetFamily:POM121,uniProtId:Q96HA1-1,ncbiNodeId:9606,antigenRange:1216-1249,antigenLength:1249,antigenImageFileName:PA5-103243_POM121_Q96HA1-1_Rabbit.svg,antigenImageFileNamePDP:PA5-103243_POM121_Q96HA1-1_Rabbit_PDP.jpeg,sortOrder:2},{targetFamily:POM121,uniProtId:A8CG34-1,ncbiNodeId:9606,antigenRange:1229,antigenLength:1229,antigenImageFileName:PA5-103243_POM121_A8CG34-1_Rabbit.svg,antigenImageFileNamePDP:PA5-103243_POM121_A8CG34-1_Rabbit_PDP.jpeg,sortOrder:3}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

1 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.4, with 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20°C

Shipping conditions

Wet ice

RRID

AB_2852607

Product Specific Information

Antibody detects endogenous levels of total POM121.

Target Information

POM121 (POM121 membrane glycoprotein), also known as POM121A (nuclear envelope pore membrane protein POM 121A), NUP121 (nucleoporin Nup121) or pore membrane protein of 121 kDa, is a 1,249 amino acid single-pass membrane protein that exists as three alternatively spiced isoforms and belongs to the POM121 family. Encoded by a gene that maps to human chromosome 7q11.23, POM121 is highly conserved and localizes to nucleus membrane and endoplasmic reticulum membrane. An essential component of the nuclear pore complex (NPC), POM121 is mandatory for nuclear envelope formation and may play a role in biogenesis of the NPC. POM121 associates with the central spoke ring complex and is involved in anchoring components of the pore complex to the pore membrane by way of its F-X-F-G repeat-containing domain. POM121 overexpression induces the formation of cytoplasmic annulate lamellae (AL).

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.