Thermo Fisher Scientific CDCA7L Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:500-1:1,000

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CDCA7L. Recombinant protein control fragment (Product #RP-88699). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CDCA7L,uniProtId:Q96GN5-1,ncbiNodeId:9606,antigenRange:58-200,antigenLength:454,antigenImageFileName:PA5-55533_CDCA7L_Q96GN5-1_Rabbit.svg,antigenImageFileNamePDP:PA5-55533_CDCA7L_Q96GN5-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.2 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2639577

Product Specific Information

Immunogen sequence: VRFHSKYFTE ELRRIFIEDT DSETEDFAGF TQSDLNGKTN PEVMVVESDL SDDGKASLVS EEEEDEEEDK ATPRRSRSRR SSIGLRVAFQ FPTKKLANKP DKNSSSEQLF SSARLQNEKK TILERKKDCR QVIQREDSTS ESE

Highest antigen sequence identity to the following orthologs: Mouse - 60%, Rat - 57%.

Target Information

Cell division cycle-associated 7-like protein (or RAM2) is a transcription factor which plays a role in transcriptional regulation and apoptotic signaling pathways. It acts as a repressor that inhibits monoamine oxidase A (MAOA) activity and gene expression by binding to promoter. It also plays an important oncogenic role in mediating the full transforming effect of MYC in medulloblastoma cells. It may act downstream of P38-kinase and BCL-2, but upstream of CASP3/caspase-3 as well as CCND1/cyclin D1 and E2F1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.