Thermo Fisher Scientific ZNF667 Polyclonal Antibody
Human ZNF667 단백질에 특이적인 Rabbit Polyclonal Antibody로, IHC(P)에서 1:50~1:200 희석 비율로 사용 가능. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. 심장 및 뇌 조직 연구, MAPK 신호경로 관련 연구에 적합.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:50–1:200
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human ZNF667 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2650273 |
Product Specific Information
- Immunogen sequence:
APWMVEPVRR RRAPDSGSKC ETKKLPPNQC NKSGQSICQK LVSAQQKAPT RKSGCNKNSV LVKPKKGHSG K - Highest antigen sequence identity to orthologs:
Mouse – 66%, Rat – 70%
Target Information
Mipu1, also known as zinc finger protein 667 (ZNF667), encodes a nuclear-localized protein containing 14 carboxy-terminal zinc finger motifs and an amino-terminal KRAB domain.
This protein is highly expressed in heart and brain and is upregulated in rat heart after transient ischemia-reperfusion.
Overexpression studies suggest Mipu1 suppresses AP-1 and SRE transcriptional activities in the MAPK signaling pathway, potentially contributing to cardiac and vascular disease pathogenesis.
At least four isoforms of MIPU1 are known.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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