Thermo Fisher Scientific ZNF667 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human ZNF667 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ZNF667,uniProtId:Q5HYK9-1,ncbiNodeId:9606,antigenRange:71-141,antigenLength:610,antigenImageFileName:PA5-61278_ZNF667_Q5HYK9-1_Rabbit.svg,antigenImageFileNamePDP:PA5-61278_ZNF667_Q5HYK9-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2650273

Product Specific Information

Immunogen sequence: APWMVEPVRR RRAPDSGSKC ETKKLPPNQC NKSGQSICQK LVSAQQKAPT RKSGCNKNSV LVKPKKGHSG K

Highest antigen sequence identity to the following orthologs: Mouse - 66%, Rat - 70%.

Target Information

Mipu1, also known as zinc finger protein 667 or ZNF667, encodes a nuclear-localized protein containing 14 carboxy-terminal zinc finger motifs and an amino-terminal KRAB domain. This protein is highly expressed in heart and brain and is upregulated in rat heart after a transient ischemia-reperfusion procedure. Overexpression experiments suggest that Mipu1 suppresses the transcriptional activities of AP-1 and SRE in the MAPK signaling pathway and thus may play a role in the pathogenesis of cardiac and vascular disease. At least four isoforms of MIPU1 are known to exist.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.