Thermo Fisher Scientific ASXL2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human ASXL2. Recombinant protein control fragment (Product #RP-105887). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:ASXL2,uniProtId:Q76L83-1,ncbiNodeId:9606,antigenRange:409-486,antigenLength:1435,antigenImageFileName:PA5-65126_ASXL2_Q76L83-1_Rabbit.svg,antigenImageFileNamePDP:PA5-65126_ASXL2_Q76L83-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2663810

Product Specific Information

Immunogen sequence: PKSMPVSEASL IRIVPVVSQS ECKEEALQMS SPGRKEECES QGEVQPNFST SSEPLLSSAL NTHELSSILP IKCPKDE

Highest antigen sequence identity to the following orthologs - mouse 62%, rat 54%.

Target Information

Putative Polycomb group (PcG) protein. PcG proteins act by forming multiprotein complexes, which are required to maintain the transcriptionally repressive state of homeotic genes throughout development. PcG proteins are not required to initiate repression, but to maintain it during later stages of development. They probably act via methylation of histones, rendering chromatin heritably changed in its expressibility. Involved in transcriptional regulation mediated by ligand-bound nuclear hormone receptors, such as peroxisome proliferator-activated receptor gamma (PPARG). Acts as coactivator for PPARG and enhances its adipocyte differentiation-inducing activity; the function seems to involve differential recruitment of acetylated and methylated histone H3.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.