Thermo Fisher Scientific FEZ2 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human FEZ2. Recombinant protein control fragment (Product #RP-102443). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:FEZ2,uniProtId:Q9UHY8-1,ncbiNodeId:9606,antigenRange:207-347,antigenLength:353,antigenImageFileName:PA5-57491_FEZ2_Q9UHY8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-57491_FEZ2_Q9UHY8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.7 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2641596

Product Specific Information

Immunogen sequence: GSYEERVKRL SVSELNEILE EIETAIKEYS EELVQQLALR DELEFEKEVK NSFISVLIEV QNKQKEHKET AKKKKKLKNG SSQNGKNERS HMPGTYLTTV IPYEKKNGPP SVEDLQILTK ILRAMKEDSE KVPSLLTDYI L

Highest antigen sequence identity to the following orthologs: Mouse - 92%, Rat - 95%.

Target Information

Fasciculation and elongation protein zeta-2 (FEZ2) is a homolog to the mammalian FEZ1, itself an ortholog of the C. elegans UNC-76. In contrast to FEZ1, FEZ2 mRNA is widely expressed in mouse tissues. FEZ2 interacts with protein kinase C (PKC)-zeta substrate and induces neurite extension of PC12 cells when co-expressed with a constitutively active form of PKC-zeta, suggesting FEZ2 may play an important role in the morphological changes of various cells by associating with PKC-zeta in a tissue non-specific manner. FEZ2 can interact with FEZ1 through its c-terminal regions and especially its coiled-coil region. At least two isoforms of FEZ2 are known to exist.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.