Thermo Fisher Scientific PRDM2 Polyclonal Antibody
상품 옵션 정보 | ||||||||
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카탈로그 번호 | CAS 번호 | 설명 | 상태 | 단위 | 판매가 | 할인가 | 가격(VAT포함) | 수량 / 장바구니 / 찜 |
PA582218 | - | Thermo Fisher Scientific PA582218 PRDM2 Polyclonal Antibody 100 ul pk | 재고문의 | pk | 742,000원 | - | 816,200원 |
다른 상품 둘러보기
Applications
Tested Dilution
Publications
Immunohistochemistry (Paraffin) (IHC (P))
1:50-1:200
Immunocytochemistry (ICC/IF)
0.25-2 µg/mL
Product Specifications
Species Reactivity
Human
Host/Isotype
Rabbit / IgG
Class
Polyclonal
Type
Antibody
Immunogen
Recombinant protein corresponding to Human PRDM2. Recombinant protein control fragment (Product #RP-89330). if (typeof window.$mangular === undefined
|| !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{
targetFamily:
PRDM2,
uniProtId:
Q13029-1,
ncbiNodeId:
9606,
antigenRange:
1300-1433,
antigenLength:
1718,
antigenImageFileName:
PA5-82218_PRDM2_Q13029-1_Rabbit.svg,
antigenImageFileNamePDP:
PA5-82218_PRDM2_Q13029-1_Rabbit_PDP.jpeg,
sortOrder:
1}\]
; $mangular.isB2BCMGT = false
; $mangular.isEpitopesModalImageMultiSizeEnabled = true
;
View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}
Conjugate
Unconjugated Unconjugated Unconjugated
Form
Liquid
Concentration
0.1 mg/mL
Purification
Antigen affinity chromatography
Storage buffer
PBS, pH 7.2, with 40% glycerol
Contains
0.02% sodium azide
Storage conditions
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Shipping conditions
Wet ice
RRID
AB_2789379
Product Specific Information
Immunogen sequence: PPPFQYHHRN PMGIGVTATN FTTHNIPQTF TTAIRCTKCG KGVDNMPELH KHILACASAS DKKRYTPKKN PVPLKQTVQP KNGVVVLDNS GKNAFRRMGQ PKRLNFSVEL SKMSSNKLKL NALKKKNQLV QKAI
Target Information
PRDM2, a member of nuclear/histone methyltransferase superfamily, consists of an N-terminal PR domain, an Rb-binding motif, 8 Kruppel-like zinc finger motifs, Nuclear hormone-receptor binding motif and a C-terminal PR-domain binding motif. Ubiquitously expressed in low levels, PRDM2 exists in 2 isoforms, a 280 kDa RIZ1 containing PR-domain and a 250 kDa truncated RIZ2 that lacks PR-domain. A tumor suppressor with a prominent role in cell growth and differentiation, PRDM2 binds to Retinoblastoma protein, estrogen receptor, GATA-3 and TPA-responsive element (MTE) of Heme-oxygenase-1 gene and influences pathogenesis of Retinoblastoma, transcriptional regulation during neuronal differentiation, transactivation of Heme-oxygenase-1 gene and specific effector of estrogen action. It is inactivated or altered due to mutations and hypermethylation in many types of human cancers suggesting a potential biomarker.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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