Thermo Fisher Scientific RNASE3 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:500–1:1,000

ELISA

• Tested Dilution: 1 µg/mL

Product Specifications

Product Specific Information

• Positive Samples: A-549, HepG2
• Immunogen sequence:
  RSRFRVPLLH CDLINPGAQN ISNCTYADRP GRRFYVVACD NRDPRDSPRY PVVPVHLDTT I

Target Information

ECP (eosinophil cationic protein), also known as RNS3 or RNASE3 (ribonuclease, RNase A family, 3), is a 160 amino acid potent cytotoxic secretory protein that belongs to the pancreatic ribonuclease family.
ECP localizes to the granule matrix of the eosinophil and is involved in the immune response system. It acts as a cytotoxin, neurotoxin, and helminthotoxin secreted by activated human eosinophils.
ECP exhibits anti-parasitic, antibacterial, and ribonucleolytic activities. It has been suggested that ECP induces the neurotoxic effect known as the Gordon phenomenon, characterized by ataxia, muscular rigidity, paralysis, and tremor.
ECP is considered a marker of eosinophilic inflammation, with elevated levels found in active asthma and other allergic diseases.

주의사항

⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.