Thermo Fisher Scientific PTPN7 Monoclonal Antibody (OTI3B10), TrueMAB
PTPN7 단백질을 인식하는 마우스 단클론 항체로, Western blot 및 Immunocytochemistry에 적합합니다. 인간, 마우스, 랫, 개 시료에 반응하며, HEK293T 세포에서 발현된 full-length human PTPN7 단백질을 면역원으로 사용했습니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- TA503714
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:500–1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Dog, Human, Mouse, Rat |
| Host / Isotype | Mouse / IgG2b |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI3B10 |
| Immunogen | Full length human recombinant protein of human PTPN7 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.72 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate various cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation.
This gene is preferentially expressed in hematopoietic cells and acts as an early response gene in lymphokine-stimulated cells. The noncatalytic N-terminus interacts with MAP kinases to suppress their activities.
PTPN7 is involved in T cell antigen receptor signaling through dephosphorylation of MAP kinase pathway-related molecules. Two alternatively spliced transcript variants encoding different isoforms have been identified.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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