Thermo Fisher Scientific Bis-BODIPY FL C11-PC) (1,2-Bis-(4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Undecanoyl)-sn-Glycero-3-Phosphocholine)

Invitrogen™ Bis-BODIPY™ FL C11-PC

(1,2-Bis-(4,4-Difluoro-5,7-Dimethyl-4-Bora-3a,4a-Diaza-s-Indacene-3-Undecanoyl)-sn-Glycero-3-Phosphocholine)

Molecular Probes™ phospholipase substrates are dye-labeled phospholipids used to monitor phospholipase A (PLA) activity in purified enzyme preparations, cell lysates, and living cells.
Two structural variations of these substrates are available, which confer specificity for PLA1 and PLA2.
Fluorescently labeled versions of the cleavage product generated from these substrates are also available for use as standards for evaluating percentage substrate conversion in enzymatic reactions.

Fluorogenic Phospholipase A Substrates Specifications

• Label (Ex/Em): Bis-BODIPY™ FL C11-PC (∼488/530 nm)
• Specificity: PLA1 or PLA2
• Cleavage product: D3862
• Lyophilized product can be dissolved in ethanol for use
• Fluorescence measurement: microplate assays or flow cytometry

참고 자료

• Fatty Acid Analogs and Phospholipids—Section 13.2
• Probes for Lipid Metabolism and Signaling—Section 17.4
  Refer to the Molecular Probes™ Handbook for more information.

For Research Use Only. Not for human or animal therapeutic or diagnostic use.

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