Thermo Fisher Scientific CHCHD10 Polyclonal Antibody
CHCHD10 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. WB, IHC, ICC/IF에 적합하며 인간 시료에 반응. 고순도 항원 친화 크로마토그래피 정제, 장기 보관 시 -20°C 권장.
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Applications
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL | - |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 | - |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL | - |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human CHCHD10. Recombinant protein control fragment (Product #RP-91517). |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2639748 |
Product Specific Information
Immunogen sequence:
GLMAQMATTA AGVAVGSAVG HVMGSALTGA FSGGSSEPSQ PAVQQAPTPA APQPLQMGPC AYEIRQFLDC STTQSDLSLC EGFSEALKQC KYYHGLSSLP
Highest antigen sequence identity to orthologs:
- Mouse: 87%
- Rat: 89%
Target Information
CHCHD10 encodes a mitochondrial protein enriched at cristae junctions in the intermembrane space. It may play a role in maintaining cristae morphology or oxidative phosphorylation. Mutations in this gene are associated with frontotemporal dementia and/or amyotrophic lateral sclerosis-2. Alternative splicing results in multiple transcript variants, and related pseudogenes are found on chromosomes 7 and 19.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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