Thermo Fisher Scientific CHCHD10 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

0.04-0.4 µg/mL

-

Immunohistochemistry (Paraffin) (IHC (P))

1:200-1:500

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CHCHD10. Recombinant protein control fragment (Product #RP-91517). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CHCHD10,uniProtId:Q8WYQ3-1,ncbiNodeId:9606,antigenRange:43-142,antigenLength:142,antigenImageFileName:PA5-51935_CHCHD10_Q8WYQ3-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51935_CHCHD10_Q8WYQ3-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2639748

Product Specific Information

Immunogen sequence: GLMAQMATTA AGVAVGSAVG HVMGSALTGA FSGGSSEPSQ PAVQQAPTPA APQPLQMGPC AYEIRQFLDC STTQSDLSLC EGFSEALKQC KYYHGLSSLP

Highest antigen sequence identity to the following orthologs: Mouse - 87%, Rat - 89%.

Target Information

CHCHD10 encodes a mitochondrial protein that is enriched at cristae junctions in the intermembrane space. It may play a role in cristae morphology maintenance or oxidative phosphorylation. Mutations in this gene cause frontotemporal dementia and/or amyotrophic lateral sclerosis-2. Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 7 and 19.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.