Thermo Fisher Scientific NSMCE2 Monoclonal Antibody (OTI6A6), TrueMAB
NSMCE2 단백질을 표적으로 하는 Mouse IgG2a 단클론 항체로, Western blot, ICC/IF, Flow cytometry에 사용 가능. 인간 단백질에 반응하며, 액상 형태로 제공. 연구용으로 DNA 손상 복구 관련 단백질 분석에 적합.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000
Immunocytochemistry (ICC/IF)
- Tested Dilution: 1:100
Flow Cytometry (Flow)
- Tested Dilution: 1:100
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI6A6 |
| Immunogen | Full length human recombinant protein of human NSMCE2 produced in E.coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.52 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes the large subunit of DNA damage-binding protein which is a heterodimer composed of a large and a small subunit. This protein functions in nucleotide-excision repair. Its defective activity causes the repair defect in patients with xeroderma pigmentosum complementation group E (XPE). However, mutation analysis is required to demonstrate whether the defect in XPE patients is in this gene or in the gene encoding the small subunit. In addition, Best vitelliform macular dystrophy is mapped to the same region as this gene on 11q, but no sequence alterations of this gene are demonstrated in Best disease patients.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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