Thermo Fisher Scientific LPHN2 Polyclonal Antibody

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human LPHN2 if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:LPHN2,uniProtId:O95490-1,ncbiNodeId:9606,antigenRange:1286-1365,antigenLength:1459,antigenImageFileName:PA5-65359_LPHN2_O95490-1_Rabbit.svg,antigenImageFileNamePDP:PA5-65359_LPHN2_O95490-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2662297

Product Specific Information

Immunogen sequence: PVKPVIGGSSS EDDAIVADAS SLMHSDNPGL ELHHKELEAP LIPQRTHSLL YQPQKKVKSE GTDSYVSQLT AEAEDHLQS

Highest antigen sequence identity to the following orthologs - mouse 93%, rat 91%.

Target Information

The Latrophilin family of G protein-coupled receptors consists of three members, latrophilin-1, 2 and 3, each of which displays distinct tissue distribution and function. Latrophilin-1, the most characterized member of this family, acts as a receptor for a-latrotoxin, a component of venom from the black widow spider. Binding of a-latrotoxin to latrophilin-1 triggers synaptic vesicle exocytosis via both Ca2+-dependent and -independent mechanisms, resulting in vesicle depletion. Latrophilin-1 is abundant in brain and present in endocrine cells. Latrophilin-3 is also brain-specific, whereas latrophilin-2 expression is ubiquitous.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.