Thermo Fisher Scientific LPHN2 Polyclonal Antibody
Rabbit 유래 다클론 항체로, 인간 LPHN2 단백질을 인식합니다. 비결합(Unconjugated) 상태의 액상 시약으로 제공되며, 0.3 mg/mL 농도입니다. 단기 4°C, 장기 -20°C 보관 권장. 연구용으로만 사용 가능합니다.
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Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human LPHN2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2662297 |
Product Specific Information
Immunogen sequence:
PVKPVIGGSSS EDDAIVADAS SLMHSDNPGL ELHHKELEAP LIPQRTHSLL YQPQKKVKSE GTDSYVSQLT AEAEDHLQS
Highest antigen sequence identity to the following orthologs:
- Mouse: 93%
- Rat: 91%
Target Information
The Latrophilin family of G protein-coupled receptors consists of three members: latrophilin-1, -2, and -3, each displaying distinct tissue distribution and function.
Latrophilin-1, the best characterized, acts as a receptor for α-latrotoxin, a component of black widow spider venom. Binding of α-latrotoxin to latrophilin-1 triggers synaptic vesicle exocytosis via both Ca²⁺-dependent and -independent mechanisms, resulting in vesicle depletion.
Latrophilin-1 is abundant in the brain and present in endocrine cells. Latrophilin-3 is also brain-specific, whereas latrophilin-2 expression is ubiquitous.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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