Thermo Fisher Scientific TNN Polyclonal Antibody
TNN 단백질을 인식하는 Rabbit Polyclonal Antibody로, Western blot과 IHC(Paraffin) 검증 완료. Human과 Mouse 시료에 반응하며, Protein A 및 항원 친화 크로마토그래피로 정제됨. 연구용으로 세포 이동, 신경 돌기 성장 및 암 관련 연구에 적합.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:10–1:50 |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide between amino acids 587–615 from the central region of human TNN |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Protein A, Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | 0.09% sodium azide |
| Storage Conditions | Store at 4 °C for short term; for long term, store at −20 °C and avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2634063 |
Target Information
Extracellular matrix protein that appears to act as a ligand for ITGA8:ITGB1, ITGAV:ITGB1, and ITGA4:ITGB1. It is involved in neurite outgrowth and cell migration in hippocampal explants. During endochondral bone formation, it inhibits proliferation and differentiation of proteoblasts mediated by canonical WNT signaling. In tumors, it stimulates angiogenesis through endothelial cell elongation, migration, and sprouting. Expressed in most mammary tumors and may facilitate tumorigenesis by supporting the migratory behavior of breast cancer cells. [UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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