Thermo Fisher Scientific SLC30A8 Polyclonal Antibody
인간 SLC30A8 단백질을 인식하는 토끼 폴리클로날 항체로, IHC(P)에서 1:500~1:1,000 희석 비율로 사용 가능. 아연 수송체 단백질 연구 및 제2형 당뇨병 관련 유전자 연구에 적합. 항원 친화 크로마토그래피로 정제된 고품질 항체.
- 카탈로그번호
- PA584993
- 판매단위
- pk
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:500–1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SLC30A8 (amino acids 315–369) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.3 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2792142 |
Product Specific Information
Immunogen sequence:
LSAHVATAAS RDSQVVRREI AKALSKSFTM HSLTIQMESP VDQDPDCLFC EDPCD
Target Information
Slc30A8 is a zinc efflux transporter involved in the accumulation of zinc in intracellular vesicles and is expressed at a high level in the pancreas, particularly in islets of Langerhans. It co-localizes with insulin in the secretory granules of insulin-secreting INS-1 cells.
Allelic variants of Slc30A8 have been identified as major genetic risk factors for the development of Type 2 diabetes, but no genetic association has been found with Type 1 diabetes.
Slc30A8 expression in β-cells is influenced by cytokine expression, particularly IFN-gamma and IL-1 beta.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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