Thermo Fisher Scientific DRIP130 Polyclonal Antibody, Biotin
DRIP130 단백질을 인식하는 Biotin 결합 Rabbit Polyclonal Antibody로, WB, IHC, ELISA, IP 등에 사용 가능. Human, Mouse, Rat 등 다양한 종에 반응하며 고순도 Affinity chromatography로 정제됨. 연구용으로 안정적인 신호 검출에 적합.
- 카탈로그번호
- MED23-BIOTIN
- 판매단위
- pk
카탈로그
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:1,000 |
| Immunohistochemistry (IHC) | 1:50–1:250 |
| ELISA | 1:10,000 |
| Immunoprecipitation (IP) | 1:50–1:250 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Non-human primate, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide within amino acid region 650–700 on MED23 protein (CRSP130, UniProt ID: Q9ULK4-1) |
| Conjugate | Biotin |
| Form | Liquid |
| Concentration | 0.5–1.5 mg/mL |
| Purification | Affinity chromatography |
| Storage Buffer | Proprietary buffer, pH 7.4–7.8, with 0.5% BSA, 30% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
CRSP is ubiquitously expressed in various tissues and functions as a multimeric complex consisting of nine distinct subunits. Several members of the CRSP family share sequence similarity with components of yeast transcriptional mediator proteins, including CRSP150 (related to yeast Rgr1) and CRSP70 (similar to elongation factor TFIIS). CRSP77 and CRSP150 are also related to proteins within the murine mediator complex, while CRSP130 and CRSP34 are largely unrelated to either murine or yeast proteins. CRSP subunits associate with larger multimeric co-activator complexes such as ARC/DRI, which binds directly to SREBP and nuclear hormone receptors to facilitate transcription, and with NAT, a polymerase II-interacting complex that represses activated transcription.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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