Thermo Fisher Scientific CDH4 Polyclonal Antibody
Human, Mouse, Rat에서 반응하는 CDH4 폴리클로날 항체로 Western Blot과 ELISA에 사용 가능. Rabbit IgG 기반 비결합형 항체이며, PBS/glycerol 저장 완충액에 포함. 세포막 단백질 CDH4 검출에 적합한 연구용 시약.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:1,000–1:2,000 |
| ELISA | 1 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant fusion protein containing a sequence corresponding to amino acids 757–916 of human CDH4 (NP_0017852) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1.44 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 50% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2804564 |
Product Specific Information
Immunogen sequence:
KRREKERHTK QLLIDPEDDV RDNILKYDEE GGGEEDQDYD LSQLQQPEAM GHVPSKAPGV RRVDERPVGA EPQYPIRPMV PHPGDIGDFI NEGLRAADND PTAPPYDSLL VFDYEGSGST AGSVSSLNSS SSGDQDYDYL NDWGPRFKKL ADMYGGGEED
Positive Samples: HepG2, Mouse brain, Mouse thymus, Rat brain, Rat skeletal muscle
Cellular Location: Cell membrane, Single-pass type I membrane protein
Target Information
CDH4 is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region, and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Studies have shown stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines, providing evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene.
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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