
Thermo Fisher Scientific BAIAP2 Monoclonal Antibody (OTI 1D9)
BAIAP2 단백질을 인식하는 Mouse IgG1 단일클론 항체. WB, IHC, ICC/IF, Flow Cytometry에 사용 가능. 인간 시료 반응성. 고순도 친화 크로마토그래피 정제. 연구용으로만 사용.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:150 |
| Immunocytochemistry (ICC/IF) | 1:100 |
| Flow Cytometry (Flow) | 1:100 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI 1D9 |
| Immunogen | Full length human recombinant protein of BAIAP2 produced in HEK293T cell |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.65 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS, pH 7.3, with 1% BSA, 50% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
| RRID | AB_2722888 |
Target Information
The protein encoded by this gene has been identified as a brain-specific angiogenesis inhibitor (BAI1)-binding protein. This adaptor protein links membrane-bound G-proteins to cytoplasmic effector proteins. It functions as an insulin receptor tyrosine kinase substrate, suggesting a role for insulin in the central nervous system. It also associates with a downstream effector of Rho small G proteins, which is related to stress fiber and cytokinesis formation. This protein participates in lamellipodia and filopodia formation in motile cells and may influence neuronal growth-cone guidance. Additionally, it interacts with the dentatorubral-pallidoluysian atrophy gene, associated with an autosomal dominant neurodegenerative disease. Alternative splicing results in multiple transcript variants encoding distinct isoforms.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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