Thermo Fisher Scientific CNGA4 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Protein Epitope Signature Tag (PrEST) antigen sequence. Antigen range: 514-567. Recombinant protein control fragment (Product #RP-109765). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CNGA4,uniProtId:Q8IV77-1,ncbiNodeId:9606,antigenRange:514-567,antigenLength:575,antigenImageFileName:PA5-145067_CNGA4_Q8IV77-1_Rabbit.svg,antigenImageFileNamePDP:PA5-145067_CNGA4_Q8IV77-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.3 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_3091934

Product Specific Information

Immunogen sequence: LLAELESSAL KIAYRIERLE WQTREWPMPE DLAEADDEGE PEEGTSKDEE GRAS

Antigen sequence identity: Mouse 83%; Rat 87%

Target Information

Second messenger, cAMP, causes the opening of cation- selective cyclic nucleotide-gated (CNG) channels and depolarization of the neuron (olfactory sensory neurons, OSNs). CNGA4 is the modulatory subunit of this channel which is known to play a central role in the transduction of odorant signals and subsequent adaptation. By accelerating the calcium-mediated negative feedback in olfactory signaling it allows rapid adaptation to odor stimulation and extends its range of odor detection.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.