Thermo Fisher Scientific CRSP6 Monoclonal Antibody (1B5)
CRSP6 단백질을 인식하는 Mouse IgG1 단클론 항체로, Western blot, ICC/IF, ELISA 등에 사용 가능. 인간 단백질에 반응하며, GST 태그가 결합된 재조합 단백질을 면역원으로 제작. 연구용으로만 사용 가능.
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Applications
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1–5 µg/mL |
| Immunocytochemistry (ICC/IF) | 10 µg/mL |
| ELISA | 3 ng/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1B5 |
| Immunogen | CRSP6 (AAH21101, 551–651 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid freeze/thaw cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
FSNHVGLGPI ESIGNASAIT VASPSGDYAI SVRNGPESGS KIMVQFPRNQ CKDLPKSDVL QDNKWSHLRG PFKEVQWNKM EGRNFVYKME LLMSALSPCL L
Target Information
The activation of gene transcription is a multistep process triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by CRSP6 is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein also participates in other multisubunit complexes, such as thyroid hormone receptor (TR)–associated proteins, which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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