Thermo Fisher Scientific Phospho-M2 Muscarinic Acetylcholine Receptor (Thr307, Ser309) Polyclonal Antibody
인산화된 M2 무스카린 아세틸콜린 수용체(Thr307, Ser309)를 인식하는 토끼 폴리클로날 항체입니다. Western blot에 적합하며, 항원 친화 크로마토그래피로 정제되었습니다. 인간 시료에 반응하며, 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
- 카탈로그번호
- 7TM0014D
- 판매단위
- pk
카탈로그
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Applications
Western Blot (WB)
- Tested Dilution: 1:1,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | A synthetic phosphopeptide derived from human M2 around the phosphorylation site of Thr307/Ser309. |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Dulbecco’s PBS, pH 7.4 |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice (domestic); Dry ice (international) |
Target Information
Muscarinic cholinergic receptor 2 (CHRM2) is an acetylcholine receptor that may function as a presynaptic autoreceptor inhibiting acetylcholine release. The M2 receptor is also implicated in smooth muscle contractility. In Alzheimer’s disease, selective loss of M2 receptors occurs in cortical and hippocampal regions. Increased M2 receptor heterozygosity has been associated with depression in women. The M2 receptor is expressed in various brain regions including the cerebellum, cerebral cortex, hippocampus, medulla, striatum, and thalamus, as well as in lung and prostate.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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