Thermo Fisher Scientific RPAP1 Polyclonal Antibody

Applications

Western Blot (WB)

• Tested Dilution: 1:1,000–1:3,000

Product Specifications

Product Specific Information

Antibody detects endogenous levels of total RPAP1.

Target Information

RNA polymerases transcribe nuclear genes for ribosomal RNA and are integral components of ribosomal biogenesis.
RNA polymerase I (Pol I) is located in the nucleolus and transcribes class I genes, which code for large ribosomal RNA.
RNA polymerase II (Pol II) synthesizes mRNA.
RNA polymerase III (Pol III) transcribes class III genes, encoding small ribosomal RNA molecules including tRNA and 5S rRNA.

RPAP1 (RNA polymerase II associated protein 1) is a 1,393 amino acid nuclear protein that connects Pol II to acetylated Histone H3 and regulators of protein complex formation.
A member of the RPAP1 family, RPAP1 exists as three alternatively spliced isoforms encoded by a gene that maps to human chromosome 15q15.1.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.