Thermo Fisher Scientific FBXO3 Polyclonal Antibody
Rabbit polyclonal antibody against human FBXO3. Validated for ICC/IF applications. Antigen affinity purified and supplied in PBS with 40% glycerol. Ideal for research use in ubiquitin-protein ligase complex studies.
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Applications
- Immunocytochemistry (ICC/IF): 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human FBXO3. Recombinant protein control fragment (Product # RP-104544) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping conditions | Wet ice |
| RRID | AB_2665110 |
Product Specific Information
Immunogen sequence:
IGCKLPDDYRC SYRIHNGQKL VVPGLLGSMA LSNHYRSEDL LDVDTAAGGF QQRQGLKYCL PLTFCIHTGL SQYIAVEAAE GRNKNEVFYQ CPDQMARNPA AIDMFIIGAT FTDWFTSYVK NVVSGGFPII RDQIFRYVHD PECV
Highest antigen sequence identity to the following orthologs:
- Mouse: 99%
- Rat: 99%
Target Information
FBXO3 encodes a member of the F-box protein family, characterized by an approximately 40 amino acid F-box motif. These proteins form part of the ubiquitin protein ligase complex (SCFs: SKP1-cullin-F-box), which functions in phosphorylation-dependent ubiquitination.
F-box proteins are classified into three groups:
- Fbws – contain WD-40 domains
- Fbls – contain leucine-rich repeats
- Fbxs – contain other interaction modules or no recognizable motifs
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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