Thermo Fisher Scientific NKG2C Polyclonal Antibody
Thermo Fisher Scientific의 NKG2C Polyclonal Antibody는 인간 시료에 반응하는 Rabbit IgG 항체로, Western blot에 적합합니다. 합성 펩타이드(aa 1–45)를 면역원으로 사용했으며, 항원 친화 크로마토그래피로 정제되었습니다. 연구용으로만 사용 가능합니다.
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Applications
- Western Blot (WB): 1:500–1:3,000
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to a region within amino acids 1–45 of NKG2-C |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.56 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | 0.1M Tris glycine, pH 7, with 10% glycerol |
| Contains | 0.01% thimerosal |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2546313 |
Product Specific Information
- Recommended positive control: K562
- Predicted reactivity: Rhesus Monkey (100%), Chimpanzee (100%)
- Store product as a concentrated solution.
- Centrifuge briefly prior to opening the vial.
Target Information
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They also regulate specific humoral and cell-mediated immunity.
The protein encoded by this gene belongs to the killer cell lectin-like receptor (NKG2) family, a group of transmembrane proteins preferentially expressed in NK cells. These proteins have a type II membrane orientation and a C-type lectin domain.
NKG2C forms a complex with KLRD1/CD94 and is involved in recognition of MHC class I HLA-E molecules in NK cells. The genes of the NKG2 family form a killer cell lectin-like receptor gene cluster on chromosome 12. Four alternatively spliced transcript variants encoding two distinct isoforms have been observed.
Safety Information
⚠ WARNING: This product can expose you to chemicals including mercury, which is known to the State of California to cause birth defects or other reproductive harm.
For more information, visit www.P65Warnings.ca.gov.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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