Thermo Fisher Scientific EWSR1 Monoclonal Antibody (OTI2B3)
EWSR1 단백질을 인식하는 Thermo Fisher Scientific의 단클론 항체로, WB 및 IHC(P) 실험에 적합. 인간 시료 반응성, Mouse IgG1 형식. 고순도 친화 크로마토그래피 정제, PBS/글리세롤 버퍼 보존. 연구용으로만 사용 가능.
- 카탈로그번호
- TA813053
- 판매단위
- pk
카탈로그
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Applications
- Western Blot (WB): 1:500
- Immunohistochemistry (Paraffin) (IHC (P)): 1:500
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG1 |
| Class | Monoclonal |
| Type | Antibody |
| Clone | OTI2B3 |
| Immunogen | Human recombinant protein fragment corresponding to amino acids 256–447 of human EWSR1 (NP_005234) produced in E. coli |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Affinity chromatography |
| Storage buffer | PBS with 50% glycerol, 1% BSA |
| Contains | 0.02% sodium azide |
| Storage conditions | -20°C |
| Shipping conditions | Ambient (domestic); Wet ice (international) |
Target Information
This gene encodes a multifunctional protein involved in various cellular processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors result in chimeric proteins involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor. Mutations, particularly translocations, are known to cause Ewing sarcoma and other tumors. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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