Himedia Human Recombinant Fibroblast Growth Factor, basic Source : E.coli Cell Culture Tested
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Human Recombinant Fibroblast Growth Factor, basic Source : E.coli Cell Culture Tested
Details
Basic Fibroblast Growth Factor (bFGF) is one of the 23 known members of FGF family. Because of its capacity to bind heparin it is also known as heparin binding factor. This heparin binding capacity enhances growth-factor ligand interaction. bFGF acts through FGF receptor 1b, 1c, 2c, 3c and 4. In general, fibroblast growth factors are potent mitogens for vascular and capillary endothelial cells. Basic FGF promotes differentiation and proliferation of wide variety of cells including mesenchymal, neuroectodermal, mesodermal and endothelial cells. It has been used to enhance the survival of new cell lines derived from primary cultures and also to eliminate the use of feeder cells during hybridoma cloning.
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