Thermo Fisher Scientific SP100 Polyclonal Antibody
Thermo Fisher Scientific의 SP100 Polyclonal Antibody는 인간 SP100 단백질을 인식하는 토끼 IgG 항체로, IHC(P) 및 ICC/IF 실험에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며 PBS/glycerol buffer에 보관됩니다. 연구용으로만 사용 가능합니다.
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Applications
Immunohistochemistry (Paraffin) (IHC (P))
- Tested Dilution: 1:200–1:500
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
- Publications: View 1 publication
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Published Species | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant protein corresponding to Human SP100 (Product #RP-91588) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term; for long term, store at -20°C avoiding freeze/thaw cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2647755 |
Product Specific Information
Immunogen sequence:
YKGFENVIHD KLPLQESEEE EREERSGLQL SLEQGTGENS FRSLTWPPSG SPSHAGTTPP ENGLSEHPCE TEQINAKRKD TTSDKDDSLG SQQTNEQCAQ KAEPTESCEQ IAVQVNNGDA GREMPCPL
Highest antigen sequence identity to the following orthologs:
- Mouse: 24%
- Rat: 24%
Target Information
This gene encodes a subnuclear organelle and major component of the PML (promyelocytic leukemia)-SP100 nuclear bodies.
PML and SP100 are covalently modified by the SUMO-1 modifier, which is crucial to nuclear body interactions.
The encoded protein binds heterochromatin proteins and may play roles in tumorigenesis, immunity, and gene regulation.
Alternatively spliced variants have been identified, one encoding a high-mobility group protein.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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