Thermo Fisher Scientific CCDC123 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CCDC123. Recombinant protein control fragment (Product #RP-102870). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CCDC123,uniProtId:Q96ST8-1,ncbiNodeId:9606,antigenRange:695-775,antigenLength:783,antigenImageFileName:PA5-58767_CCDC123_Q96ST8-1_Rabbit.svg,antigenImageFileNamePDP:PA5-58767_CCDC123_Q96ST8-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.7 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2639372

Product Specific Information

Immunogen sequence: QVLKDKQEVL DQALQQNREM EGELEVIWES TFRENRRIRE LLQDTLTRTG VQDNPRALVA PSLNGVSQAD LLDGCDVCSY D

Highest antigen sequence identity to the following orthologs: Mouse - 52%, Rat - 51%.

Target Information

CCDC123 (as known as CEP123), also named as CEP89, is a new player in the process of primary ciliogenesis and it also plays a role in mitochondrial metabolism where it may modulate complex IV activity. It has been shown that CEP123 is localized to the distal appendages of the mother centriole and the localization of CEP123 is cell cycle-dependent with its levels decreasing during mitosis. CEP123 depletion can cause defects in ciliary vesicle formation and prevent the formation of a ciliary vesicle at the distal end of the mother centriole. It is possible that CEP123 is involved in regulating the recruitment of membranes to the centrosome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.