Thermo Fisher Scientific DGAT2 Polyclonal Antibody
DGAT2 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody로, WB, IHC, ICC, ELISA 등 다양한 응용에 적합합니다. Human, Mouse, Rat 반응성을 가지며 Protein A로 정제된 액상 형태로 제공됩니다. 연구용으로만 사용 가능합니다.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:100–1:500 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human DGAT2 (amino acids 251–360) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | −20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Acyl-coenzyme A:diacylglycerol acyltransferase (DGAT), also known as DGAT1 and ARGP1, is a microsomal enzyme involved in the synthesis of fatty acids into triglycerides. DGAT1 catalyzes the terminal and only committed step in triacylglycerol synthesis using diacylglycerol (DAG) and fatty acyl CoA as substrates. It plays a key role in cellular diacylglycerol metabolism and physiological processes such as intestinal fat absorption, lipoprotein assembly, adipose tissue formation, and lactation.
DGAT2, which has no homology to DGAT1, differs in that its activity is inhibited by MgCl₂ in vitro. DGAT2 is primarily expressed in liver and white adipose tissue, suggesting its importance in mammalian triglyceride metabolism.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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