Thermo Fisher Scientific PARK2 Polyclonal Antibody, MaxPab

Applications

Western Blot (WB)

• Tested Dilution: 1–5 µg/mL
• Publications: []

in situ PLA (PLA)

• Tested Dilution: 1:1200
• Publications: []

Product Specifications

Product Specific Information

Sequence of this protein is as follows:
MIVFVRFNSS HGFPVEVDSD TSIFQLKEVV AKRQGVPADQ LRVIFAGKEL RNDWTVQNCD LDQQSIVHIV QRPWRKGQEM NATGGDDPRN AAGGCEREPQ SLTRVDLSSS VLPGDSVGLA VILHTDSRKD SPPAGSPAGR SIYNSFYVYC KGPCQRVQPG KLRVQCSTCR QATLTLTQGP SCWDDVLIPN RMSGECQSPH CPGTSAEFFF KCGAHPTSDK ETSVALHLIA TNSRNITCIT CTDVRSPVLV FQCNSRHVIC LDCFHLYCVT RLNDRQFVHD PQLGYSLPCV GTGDTVVLRG ALGGFRRGVA GCPNSLIKEL HHFRILGEEQ YNRYQQYGAE ECVLQMGGVL CPRPGCGAGL LPEPDQRKVT CEGGNGLGCG YGQRRT

Target Information

The precise function of the Parkin gene is unknown; however, the encoded protein is a component of a multiprotein E3 ubiquitin ligase complex that mediates the targeting of substrate proteins for proteasomal degradation.
Mutations in this gene are known to cause Parkinson disease and autosomal recessive juvenile Parkinson disease.
Alternative splicing produces multiple transcript variants encoding distinct isoforms.
Additional splice variants have been described but currently lack transcript support.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.