Thermo Fisher Scientific CRLF2 Polyclonal Antibody
CRLF2 단백항체로 Mouse 및 Rat 반응성을 가지며, Rabbit Polyclonal IgG 형태입니다. WB, IHC, ICC, ELISA 등 다양한 실험에 사용 가능하며, Protein A로 정제된 액상 형태입니다. 연구용으로만 사용되며, -20°C에서 보관합니다.
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Thermo Fisher Scientific CRLF2 Polyclonal Antibody
Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:300–1:1,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | Assay-dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Mouse, Rat |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from mouse CRLF2, amino acids 251–350 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
Thymic stromal lymphopoietin (TSLP) is an important factor that drives dendritic cell maturation and activation. It plays a role in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis, and induction of CD4+ T cell-mediated allergic reactions. TSLP supports the growth and differentiation of fetal liver and adult B cell progenitors to the IgM-positive stage. Its receptor, TSLP-R, binds TSLP with low affinity in transfected cells, but co-transfection with IL-7R-alpha cDNA results in high-affinity binding and formation of a functional heteromeric complex. This receptor requires STAT5 for TSLP-mediated signal transduction and is inhibited by SOCS-1.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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