Thermo Fisher Scientific TSC22D1 Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant Human TSC22. Recombinant protein control fragment (Product #RP-108113). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TSC22D1,uniProtId:Q15714-1,ncbiNodeId:9606,antigenRange:628-712,antigenLength:1073,antigenImageFileName:PA5-67456_TSC22D1_Q15714-1_Rabbit.svg,antigenImageFileNamePDP:PA5-67456_TSC22D1_Q15714-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2663367

Product Specific Information

Immunogen sequence: QYGQQQPMVST QMAPGHVKSV TQNPASEYVQ QQPILQTAMS SGQPSSAGVG AGTTVIPVAQ PQGIQLPVQP TAVPAQPAGA SVQP

Highest antigen sequence identity to the following orthologs - mouse 74%, rat 78%.

Target Information

TSC22 domain family protein, or TSC22, is a transcription factor that belongs to the large family of early response genes. This transcriptional repressor is known to act on the C-type natriuretic peptide (CNP) promoter. TSC22 belongs to the TSC-22/Dip/Bun family and is an intracellular protein that may be found in the cytoplasm or nucleus. This transcription factor is known to regulate cell growth, differentiation and cell death and is involved in modulating the transcriptional activity of Smad3 and Smad4. This protein is ubiquitously expressed in most tissues and widely in both fetal and adult tissues. It is generally expressed in aortic endothelial cells, and induced by cytokines, including TGFB. These proteins may be possible therapeutic targets of leukemia and prostate cancer.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.