Thermo Fisher Scientific TSC22D1 Polyclonal Antibody
Human TSC22D1 단백질을 인식하는 Rabbit Polyclonal Antibody로 ICC/IF에 적합. 항원 친화 크로마토그래피로 정제되어 높은 특이성과 재현성을 제공. PBS 및 글리세롤 기반으로 안정적이며 장기 보관 가능. 연구용으로 세포 성장, 분화, 사멸 관련 연구에 활용.
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Applications
Immunocytochemistry (ICC/IF)
- Tested Dilution: 0.25–2 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human TSC22. Recombinant protein control fragment (Product #RP-108113) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.05 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2663367 |
Product Specific Information
Immunogen sequence:
QYGQQQPMVST QMAPGHVKSV TQNPASEYVQ QQPILQTAMS SGQPSSAGVG AGTTVIPVAQ PQGIQLPVQP TAVPAQPAGA SVQP
- Highest antigen sequence identity to orthologs: mouse 74%, rat 78%
Target Information
TSC22 domain family protein (TSC22) is a transcription factor belonging to the early response gene family. It acts as a transcriptional repressor on the C-type natriuretic peptide (CNP) promoter and is part of the TSC-22/Dip/Bun family.
This intracellular protein localizes to the cytoplasm or nucleus and regulates cell growth, differentiation, and apoptosis.
TSC22 modulates Smad3 and Smad4 transcriptional activity and is ubiquitously expressed in both fetal and adult tissues, including aortic endothelial cells.
Expression is induced by cytokines such as TGFB, and the protein may serve as a potential therapeutic target for leukemia and prostate cancer.
For Research Use Only.
Not for use in diagnostic procedures or resale without express authorization.
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