Thermo Fisher Scientific MRCK alpha Polyclonal Antibody
Human MRCK alpha 단백질을 인식하는 Goat Polyclonal 항체. IHC(P)에서 검증됨. 액상 형태, 0.5 mg/mL 농도, TBS 버퍼(pH 7.3)와 0.5% BSA 포함. -20°C 보관, 동결/해동 반복 피할 것. 연구용으로만 사용 가능.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Immunohistochemistry (Paraffin) (IHC (P)) | 3.75 µg/mL |
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Goat / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Peptide with sequence SGEVRLRQLEQFI-C (aa 2–14) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Ammonium sulfate precipitation |
| Storage Buffer | TBS, pH 7.3, with 0.5% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2932771 |
Product Specific Information
- This antibody is expected to recognize both reported Human isoforms (NP_055641.3 and NP_003598.2).
- Tested in Peptide ELISA: antibody detection limit dilution 1:16,000.
Target Information
CDC42BPA (MRCKA) is a serine/threonine kinase involved in actin cytoskeleton assembly and organization.
Three independent coiled-coil domains and the N-terminal region preceding the kinase domain mediate intermolecular interactions leading to MRCK alpha multimerization.
Transautophosphorylation is critical for regulating MRCK alpha catalytic activities.
Binding of phorbol esters releases autoinhibition, allowing N-terminal dimerization and subsequent kinase activation.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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