Thermo Fisher Scientific ARAP1 Polyclonal Antibody
ARAP1 단백질을 인식하는 Thermo Fisher Scientific의 Rabbit Polyclonal Antibody. Western blot, IHC, ICC/IF 등 다양한 응용에 적합. 인간 시료 반응성, 항원 친화 크로마토그래피로 정제. 장기 보관 시 -20°C 권장.
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Applications and Tested Dilutions
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 0.04–0.4 µg/mL |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:200–1:500 |
| Immunocytochemistry (ICC/IF) | 0.25–2 µg/mL |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Recombinant Human ARAP1. Recombinant protein control fragment (Product #RP-105502) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.2 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS, pH 7.2, with 40% glycerol |
| Contains | 0.02% sodium azide |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2664458 |
Product Specific Information
Immunogen sequence:
SLPSTIAAPHP MDGPPGGSTP VTPVIKAGWL DKNPPQGSYI YQKRWVRLDT DHLRYFDSNK DAYSKRFISV ACISHVAAIG DQKFEVITNN RTFAFRAESD VERK
Highest antigen sequence identity to the following orthologs:
- Mouse: 80%
- Rat: 82%
Target Information
ARAP1 (angiotensin II type 1 receptor-associated protein) is an adaptor protein with ArfGAP and RhoGAP activities, containing five PH domains and ankyrin repeats. It acts as a link between phosphoinositide-, Arf-, and Rho-mediated cell signaling. ARAP1 supports plasma membrane recycling of angiotensin II type 1 receptor (AT1) and regulates cell-specific trafficking of pro-death receptor TRAIL-R1 (DR4), promoting TRAIL-induced apoptosis in certain cell types. It also influences cell spreading.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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