Thermo Fisher Scientific eIF3H/EIF3S3 Polyclonal Antibody
Thermo Fisher Scientific의 eIF3H/EIF3S3 Polyclonal Antibody는 인간 및 마우스 시료에 반응하는 Rabbit IgG 기반 항체로, Western blot과 Immunoprecipitation에 적합합니다. 항원 친화 크로마토그래피로 정제되었으며, 단백질 번역 개시 복합체 연구에 활용됩니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–5 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human, Mouse |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 302 and 352 of human eukaryotic translation initiation factor 3 subunit H (eukaryotic translation initiation factor 3, subunit 2) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | Tris citrate/phosphate, pH 7–8 |
| Contains | 0.09% sodium azide |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
The recommended shelf life for this product is 1 year from date of receipt.
Target Information
eIF3H is a component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis.
The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC).
It stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition.
The eIF-3 complex also plays a role in disassembly and recycling of post-termination ribosomal complexes and prevents premature joining of 40S and 60S subunits prior to initiation.
Additionally, eIF3H contributes to translation of mRNAs involved in cell proliferation, differentiation, and apoptosis.
For Research Use Only.
Not for use in diagnostic procedures.
Not for resale without express authorization.
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