Thermo Fisher Scientific TRBP Recombinant Rabbit Monoclonal Antibody (ARC1792)

Applications

Tested Dilution

Publications

Western Blot (WB)

1:500-1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50-1:200

-

Immunocytochemistry (ICC/IF)

1:50-1:200

-

ELISA (ELISA)

1 µg/mL

-

Product Specifications

Species Reactivity

Human, Mouse, Rat

Host/Isotype

Rabbit / IgG

Expression System

HEK293 cells

Class

Recombinant Monoclonal

Type

Antibody

Clone

ARC1792

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 200-300 of human TARBP2 (Q15633) if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:TRBP,uniProtId:Q15633-1,ncbiNodeId:9606,antigenRange:200-300,antigenLength:366,antigenImageFileName:MA5-38184_TRBP_Q15633-1_Rabbit.svg,antigenImageFileNamePDP:MA5-38184_TRBP_Q15633-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.8 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS, pH 7.3, with 50% glycerol, 0.05% BSA

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_2898101

Product Specific Information

Positive Samples: Mouse testis, Rat brain

Immunogen sequence: RFIEIGSGTS KKLAKRNAAA KMLLRVHTVP LDARDGNEVE PDDDHFSIGV GSRLDGLRNR GPGCTWDSLR NSVGEKILSL RSCSLGSLGA LGPACCRVLS E

Target Information

TRBP belongs to the family of dsRNA-binding proteins. It consists of highly conserved 2 dsRNA-binding domains and C-terminal basic region. It is a unique cellular protein capable of binding to HIV-TAR RNA and stimulates expression of HIV-1 long terminal repeats. It also inhibits the host antiviral and anti-proliferative mechanisms by directly binding to IFN-regulated dsRNA-dependent protein kinase (PKR). TRBP associates with Ago2 protein and forms an integral component of Dicer-containing complex. It has a role in micro RNA processing and in RISC assembly. Other functions of TRBP include promoting cellular growth and tumorigenesis.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.