Thermo Fisher Scientific C1QC Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (Paraffin) (IHC (P))

1:1,000-1:2,500

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human C1QC. Recombinant protein control fragment (Product #RP-95389). if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:C1QC,uniProtId:P02747-1,ncbiNodeId:9606,antigenRange:103-234,antigenLength:245,antigenImageFileName:PA5-51583_C1QC_P02747-1_Rabbit.svg,antigenImageFileNamePDP:PA5-51583_C1QC_P02747-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.05 mg/mL

Purification

Antigen affinity chromatography

Storage buffer

PBS, pH 7.2, with 40% glycerol

Contains

0.02% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2638957

Product Specific Information

Immunogen sequence: GIPGEPGEEG RYKQKFQSVF TVTRQTHQPP APNSLIRFNA VLTNPQGDYD TSTGKFTCKV PGLYYFVYHA SHTANLCVLL YRSGVKVVTF CGHTSKTNQV NSGGVLLRLQ VGEEVWLAVN DYYDMVGIQG SD

Highest antigen sequence identity to the following orthologs: Mouse - 70%, Rat - 73%.

Target Information

This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. A deficiency in C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N-terminus, and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the C-chain polypeptide of human complement subcomponent C1q. Alternatively spliced transcript variants that encode the same protein have been found for this gene.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.