Thermo Fisher Scientific Human PRRT2 Synthetic Peptide

Applications

Control (Ctrl)

• Assay-dependent

Blocking Assay (BLOCK)

• Assay-dependent

Product Specifications

Product Specific Information

This peptide corresponds to 18 amino acids near the center of human PRRT2.
PEP-1580 can be used as a blocking peptide with polyclonal antibody PA5-34537.
For use as a blocking peptide in Western blot, incubate the peptide with equal volume of antibody for 30 min at 37ºC.

Target Information

The proline-rich transmembrane protein 2 (PRRT2) contains a proline-rich domain in its N-terminal half and is predominantly expressed in brain and spinal cord during embryonic and postnatal stages.
Mutations in PRRT2 are known to cause paroxysmal kinesigenic dyskinesia, characterized by recurrent, brief attacks of abnormal involuntary movements induced by sudden voluntary movements.
Recent studies suggest PRRT2 may also be involved in some forms of benign familial infantile epilepsy (BFIE), an autosomal dominant epilepsy syndrome.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.