Thermo Fisher Scientific ITM2B Monoclonal Antibody (1A10)
ITM2B 단백질을 인식하는 Mouse IgG2a 단클론 항체로, Western blot과 ELISA에 사용 가능. 인간 시료 반응성. PBS 기반 액상 형태로 보존제 없음. -20°C에서 보관하며 연구용으로 적합.
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- H00009445-M05
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Applications
Western Blot (WB)
- Tested Dilution: 1–5 µg/mL
ELISA
- Tested Dilution: 1 ng/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Mouse / IgG2a, kappa |
| Class | Monoclonal |
| Type | Antibody |
| Clone | 1A10 |
| Immunogen | ITM2B (NP_068839, 146–245 a.a.) partial recombinant protein with GST tag (MW of GST tag: 26 kDa) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | See Label |
| Purification | Affinity chromatography |
| Storage Buffer | PBS, pH 7.4 |
| Contains | No preservative |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Product Specific Information
Sequence of this protein is as follows:
VHDFNKKLTA YLDLNLDKCY VIPLNTSIVM PPRNLLELLI NIKAGTYLPQ SYLIHEHMVI TDRIENIDHL GFFIYRLCHD KETYKLQRRE TIKGIQKREA
Target Information
Amyloid precursor proteins are processed by beta-secretase and gamma-secretase to produce beta-amyloid peptides which form the characteristic plaques of Alzheimer disease.
This gene encodes a transmembrane protein which is processed at the C-terminus by furin or furin-like proteases to produce a small secreted peptide that inhibits beta-amyloid deposition.
Mutations that extend the C-terminal end of the encoded protein, increasing the size of the secreted peptide, are associated with familial British dementia and familial Danish dementia.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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