Thermo Fisher Scientific Human RGS22 Synthetic Peptide
Human RGS22 단백질의 N-말단 19개 아미노산 서열에 해당하는 합성 펩타이드. PA5-34426 항체의 블로킹 펩타이드로 사용 가능. PBS(pH 7.2), 0.1% BSA, 0.02% sodium azide 함유. -20°C 보관. 연구용으로만 사용.
- 카탈로그번호
- PEP1468
- 카테고리
- Protein
- 판매단위
- pk
카탈로그
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Applications
Control (Ctrl)
- Assay-dependent
Blocking Assay (BLOCK)
- Assay-dependent
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Class | Synthetic |
| Type | Peptide |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 200 µg/mL |
| Purification | Purified |
| Storage Buffer | PBS, pH 7.2, with 0.1% BSA |
| Contains | 0.02% sodium azide |
| Storage Conditions | -20°C |
Product Specific Information
This peptide corresponds to a 19 amino acid sequence near the amino terminus of human RGS22.
PEP-1468 can be used as a blocking peptide with polyclonal antibody PA5-34426.
Target Information
Regulator of G-protein signaling (RGS) proteins contain a conserved 120 amino acid RGS domain that functions as a GTPase-activating protein to reduce signaling from receptor-activated G-alpha subunits.
RGS22 is a recently identified member of this family, localized to the testis, and interacts with guanine nucleotide-binding proteins alpha 11, 12, and 13 (GNA11, GNA12, GNA13).
Although RGS22 is implicated in spermiogenesis, it is also expressed in several epithelial-origin cancer cell lines and associated with cancer metastasis. Overexpression of RGS22 in highly metastatic cancer cells decreases migration and invasiveness, suggesting its potential as a prognostic biomarker for metastasis.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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