Thermo Fisher Scientific GCOM1 Polyclonal Antibody
Thermo Fisher Scientific의 GCOM1 Polyclonal Antibody는 인간, 마우스, 랫트에 반응하는 Rabbit IgG 항체로 다양한 면역분석에 적합합니다. Western blot, IHC, ICC, ELISA 등 다중 응용 가능하며, 고순도 Protein A 정제 및 안정적 액상 형태로 제공됩니다.
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Applications and Tested Dilution
| Application | Tested Dilution |
|---|---|
| Western Blot (WB) | 1:500–1:2,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:100–1:500 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:100–1:500 |
| Immunocytochemistry (ICC/IF) | 1:50–1:200 |
| ELISA | 1:500–1:1,000 |
Product Specifications
| Specification | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Host/Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | KLH conjugated synthetic peptide derived from human GCOM1, amino acids 51–150 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Purification | Protein A |
| Storage Buffer | 0.01M TBS, pH 7.4, with 50% glycerol, 1% BSA |
| Contains | 0.02% ProClin 300 |
| Storage Conditions | -20°C |
| Shipping Conditions | Ambient (domestic); Wet ice (international) |
Target Information
MYOZAP, also known as GRINL1A, is a 54 kDa highly conserved cardiac protein strongly expressed in the heart and lung. It is a novel component of the intercalated disc and interacts with myosin phosphatase-RhoA interacting protein (MRIP), acting as an activator of Rho-dependent SRF signaling. Knockdown studies in zebrafish result in cardiomyopathy with severe dysfunction. The MYOZAP gene is part of a complex transcript unit that includes the gene for glutamate receptor, ionotropic, N-methyl D-aspartate-like 1A (GRINL1A), transcribed from an upstream promoter with two groups of alternatively spliced variants: Gup (GRINL1A upstream transcripts) and Gcom (GRINL1A combined transcripts).
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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