Thermo Fisher Scientific NFATC1 Polyclonal Antibody
NFATC1 단백질을 인식하는 Thermo Fisher의 Rabbit Polyclonal Antibody로, WB, IHC, ICC/IF, Flow Cytometry 등에 사용 가능. 인간, 마우스, 랫트 반응성. 항원 친화 크로마토그래피로 정제되었으며, 동결건조 형태로 제공.
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Applications and Tested Dilution
| Application | Tested Dilution | Publications |
|---|---|---|
| Western Blot (WB) | 0.1–0.5 µg/mL | – |
| Immunohistochemistry (IHC) | – | 1 publication |
| Immunohistochemistry (Frozen) (IHC (F)) | 0.5–1 µg/mL | – |
| Immunocytochemistry (ICC/IF) | 0.5–1 µg/mL | – |
| Flow Cytometry (Flow) | 1–3 µg/1×10^6 cells | – |
Product Specifications
| Item | Description |
|---|---|
| Species Reactivity | Human, Mouse, Rat |
| Published Species | Not Applicable |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | E. coli-derived human NFAT2 recombinant protein (Position: Q589–K652) |
| Conjugate | Unconjugated |
| Form | Lyophilized |
| Concentration | 500 µg/mL |
| Purification | Antigen affinity chromatography |
| Storage Buffer | PBS with 4 mg trehalose |
| Contains | 0.05 mg sodium azide |
| Storage Conditions | –20°C |
| Shipping Conditions | Wet ice |
| RRID | AB_2746845 |
Product Specific Information
Reconstitute with 0.2 mL of distilled water to yield a concentration of 500 µg/mL.
Target Information
NFATC1 is a component of the nuclear factor of activated T cells (NFAT) DNA-binding transcription complex. This complex includes a cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. NFAT family proteins play a key role in inducible gene transcription during immune response. NFATC1 functions as a major molecular target for immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified, which may regulate inducible expression of different cytokine genes.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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