Thermo Fisher Scientific HIV1 gp120 Polyclonal Antibody

Applications

Tested Dilution

Publications

Western Blot (WB)

Assay-dependent

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Product Specifications

Species Reactivity

Virus

Published species

Not Applicable

Host/Isotype

Goat / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Purified native gp120 from strain IIIB.

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

5.0 mg/mL

Purification

IgG fraction

Storage buffer

PBS, pH 7.2

Contains

0.1% sodium azide

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Ambient (domestic); Wet ice (international)

RRID

AB_559501

Product Specific Information

PA1-7218 detects the HIV1 gp120. This antibody does not cross-react with human T or B cells.

PA1-7218 has been successfully used in Western blot and ELISA procedures.

The PA1-7218 immunogen is purified native gp120 from strain IIIB.

Recommended storage of up to 6 months at 2-8ºC. For long term storage, aliquot and freeze. avoiding freeze/thaw cycles.

Target Information

Human immunodeficiency virus type 1 (HIV-1) entry into target cells is directed by the envelope (Env) glycoproteins, which are present on the surface of HIV-1 virion or infected cells in the form of trimers consisting of gp120/gp41 complexes. The surface subunit, gp120, initiates the entry process by interacting sequentially with the CD4 receptor and a co-receptor CCR5 or CXCR4, thereby inducing a conformational change that allows the transmembrane (TM) gp41 subunit to mediate fusion between viral and target cell membranes. Cleavage of Env into its gp120 and gp41 components is necessary for activation of its fusogenic activity.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.