Thermo Fisher Scientific AKR1B10 Polyclonal Antibody
AKR1B10 단백질을 인식하는 Thermo Fisher Scientific의 토끼 폴리클로날 항체. Western blot에 최적화되어 있으며, 인간, 마우스, 랫드 간 조직에서 양성 대조로 사용 가능. 인간 AKR1B10 100–200번 잔기 합성 펩타이드로부터 제작됨. 연구용으로만 사용.
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Applications
Western Blot (WB)
- Tested Dilution: 1 µg/mL
- Suggested Positive Control: Human, mouse, or rat liver tissue lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide corresponding to residues 100–200 of human AKR1B10 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Storage Conditions | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Shipping Conditions | Wet ice |
| RRID | AB_2224267 |
Product Specific Information
This antibody is predicted to react with chimpanzee samples based on sequence homology.
Suggested positive control: human, mouse, or rat liver tissue lysate.
Target Information
AKR1B10 is a 316 amino acid protein that catalyzes efficient reduction of aliphatic and aromatic aldehydes.
It is the first cytosolic NADP(H)-dependent retinal reductase described in humans, characterized by a novel NADP binding motif.
Due to its ability to convert glucose to sorbitol, AKR1B10 may play a role in the development of secondary diabetic complications.
It is abundantly expressed in adrenal gland, small intestine, and colon, with lower expression in liver, thymus, prostate, testis, and skeletal muscle.
Expression levels are upregulated in certain cancers such as hepatocellular carcinoma.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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