Thermo Fisher Scientific PIM2 Monoclonal Antibody (OTI8H10), TrueMAB

Applications

Tested Dilution

Publications

Western Blot (WB)

1:2,000

-

Immunohistochemistry (Paraffin) (IHC (P))

1:50

-

Immunocytochemistry (ICC/IF)

1:100

-

Flow Cytometry (Flow)

1:100

-

Immunoprecipitation (IP)

4 µg/ mL

-

Product Specifications

Species Reactivity

Human

Host/Isotype

Mouse / IgG3

Class

Monoclonal

Type

Antibody

Clone

OTI8H10

Immunogen

Full length human recombinant protein of human PIM2 produced in HEK293T cell. if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:PIM2,uniProtId:Q9P1W9-1,ncbiNodeId:9606,antigenRange:1-311,antigenLength:311,antigenImageFileName:TA501070_PIM2_Q9P1W9-1_House_mouse.svg,antigenImageFileNamePDP:TA501070_PIM2_Q9P1W9-1_House_mouse_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

View immunogen .st0{fill:#FFFFFF;} .st1{fill:#1E8AE7;}

Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.92 mg/mL

Purification

Affinity chromatography

Storage buffer

PBS with 1% BSA, 50% glycerol

Contains

0.02% sodium azide

Storage conditions

-20° C, Avoid Freeze/Thaw Cycles

Shipping conditions

Ambient (domestic); Wet ice (international)

Target Information

PIM2 is a proto-oncogene which phosphorylates BAD, which partially inhibits its apopotopic function. PIM proteins (PIM-1, PIM-2 and PIM-3) are oncogene-encoded serine/threonine kinases. PIM-2 is highly homologous to Pim-1 with similar oncogenic functions. PIM-2 is most abundantly expressed in hematopoietic tissues, spleen, thymus, and peripheral blood leukocytes, as well as in testis, small intestine, and colon. PIM2 expression is negatively regulated by growth factor depletion. Increased levels of PIM-2 has also been observed in certain cancers.

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.