Thermo Fisher Scientific CENPM Polyclonal Antibody

Applications

Tested Dilution

Publications

Immunohistochemistry (IHC)

1:50-1:200

-

Immunocytochemistry (ICC/IF)

0.25-2 µg/mL

-

Product Specifications

Host/Isotype

Rabbit / IgG

Class

Polyclonal

Type

Antibody

Immunogen

Recombinant protein corresponding to Human CENPM if (typeof window.$mangular === undefined || !window.$mangular) { window.$mangular = {}; } $mangular.antigenJson = \[{targetFamily:CENPM,uniProtId:Q9NSP4-1,ncbiNodeId:9606,antigenRange:6-81,antigenLength:180,antigenImageFileName:PA5-59969_CENPM_Q9NSP4-1_Rabbit.svg,antigenImageFileNamePDP:PA5-59969_CENPM_Q9NSP4-1_Rabbit_PDP.jpeg,sortOrder:1}\]; $mangular.isB2BCMGT = false; $mangular.isEpitopesModalImageMultiSizeEnabled = true;

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Conjugate

Unconjugated Unconjugated Unconjugated

Form

Liquid

Concentration

0.1 mg/mL

Storage conditions

Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.

Shipping conditions

Wet ice

RRID

AB_2639651

Product Specific Information

Immunogen sequence: PLDKLPGLNT ATILLVGTED ALLQQLADSM LKEDCASELK VHLAKSLPLP SSVNRPRIDL IVFVVNLHSK YSLQNT

Highest antigen sequence identity to the following orthologs: Mouse - 82%, Rat - 80%.

Target Information

The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA replaces histone H3. CENPM is an additional factor required for centromere assembly.The centromere is a specialized chromatin domain, present throughout the cell cycle, that acts as a platform on which the transient assembly of the kinetochore occurs during mitosis. All active centromeres are characterized by the presence of long arrays of nucleosomes in which CENPA (MIM 117139) replaces histone H3 (see MIM 601128). CENPM is an additional factor required for centromere assembly (Foltz et al., 2006 [PubMed 16622419]).[supplied by OMIM].

For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.