Thermo Fisher Scientific ARS2 Polyclonal Antibody
Thermo Fisher Scientific ARS2 Polyclonal Antibody는 인간 ARS2 단백질(1–50번 잔기)에 대한 토끼 IgG 폴리클로날 항체로, Western blot 및 Immunoprecipitation에 적합합니다. 액상 형태로 제공되며, 1 mg/mL 농도, 4°C 보관, 1년의 권장 유효기간을 갖습니다.
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Applications
Western Blot (WB)
- Tested Dilution: 1:2,000–1:10,000
Immunoprecipitation (IP)
- Tested Dilution: 2–10 µg/mg lysate
Product Specifications
| 항목 | 내용 |
|---|---|
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Region between residue 1 to 50 of human Arsenate Resistance Protein 2 |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 1 mg/mL |
| Storage Conditions | 4°C |
| Shipping Conditions | Wet ice |
Product Specific Information
- Recommended shelf life: 1 year from date of receipt
- Based on 100% sequence identity, this antibody is predicted to react with Zebrafish, X. laevis, Bovine, and Orangutan
Target Information
Acts as a mediator between the cap-binding complex (CBC) and the primary microRNAs (miRNAs) processing machinery during cell proliferation.
Contributes to the stability and delivery of capped primary miRNA transcripts to the processing complex containing DGCR8 and DROSHA, playing a role in RNA-mediated gene silencing (RNAi) by miRNAs.
Binds capped RNAs (m7GpppG-capped RNA) via interaction with NCBP1/CBP80 component of the CBC complex.
Involved in cell cycle progression at S phase.
Does not directly confer arsenite resistance but modulates arsenic sensitivity.
Independently promotes neural stem cell self-renewal by binding the SOX2 promoter and positively regulating its transcription.
[UniProt]
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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