Thermo Fisher Scientific Calpain 11 Polyclonal Antibody
Rabbit polyclonal antibody targeting human Calpain 11 (CAPN11). Validated for Western Blot at 0.2–1 µg/mL. Affinity purified, supplied in PBS with 2% sucrose. For research use only.
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Applications
Western Blot (WB)
- Tested Dilution: 0.2–1 µg/mL
Product Specifications
| 항목 | 내용 |
|---|---|
| Species Reactivity | Human |
| Host / Isotype | Rabbit / IgG |
| Class | Polyclonal |
| Type | Antibody |
| Immunogen | Synthetic peptide directed towards the N-terminal of human CAPN11 (aa 43–92) |
| Conjugate | Unconjugated |
| Form | Liquid |
| Concentration | 0.5 mg/mL |
| Purification | Affinity Chromatography |
| Storage Buffer | PBS with 2% sucrose |
| Contains | 0.09% sodium azide |
| Storage Conditions | -20°C, Avoid Freeze/Thaw Cycles |
| Shipping Conditions | Wet ice |
| RRID | AB_2576540 |
Product Specific Information
Peptide sequence:
NNSRLKAKGV GQHDNAQNFG NQSFEELRAA CLRKGELFED PLFPAEPSSL
Sequence homology:
Cow: 85%; Dog: 100%; Goat: 85%; Guinea Pig: 93%; Horse: 86%; Human: 100%; Mouse: 77%; Rabbit: 93%; Rat: 91%; Sheep: 85%; Zebrafish: 92%
Target Information
The calpains, including Calpain 1 (CAPN1), are calcium-activated neutral proteases that are nonlysosomal, intracellular cysteine proteases. Mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large catalytic subunits associated with a common small regulatory subunit.
This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been identified.
Diseases associated with CAPN1 include Spastic Paraplegia 76 (Autosomal Recessive) and Spasticity.
For Research Use Only. Not for use in diagnostic procedures. Not for resale without express authorization.
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